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pentobarbital will lessen the extent or effect of alosetron by affecting hepatic enzyme CYP2C9/10 metabolism. Slight/Significance Unidentified.Keep an eye on Intently (one)pentobarbital will minimize the level or effect of tofacitinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor. Lack of, or lowered response to tofa